Diagnosis and Management of Velopharyngeal Insufficiency Associated with Chromosomal Syndromes

Abstract

All congenital structural defects in the body are the result of an error in morphogenesis. Morphogenesis takes place around 25 to 29 days of intrauterine life. Chromosomal syndromes involve a phenotypically significant structural and/or numerical chromosomal abnormality. An insufficient function of the velopharyngeal sphincter induces excessive nasal… (More)

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