Diagnosis and Management of Osteopetrosis: Consensus Guidelines From the Osteopetrosis Working Group.

@article{Wu2017DiagnosisAM,
  title={Diagnosis and Management of Osteopetrosis: Consensus Guidelines From the Osteopetrosis Working Group.},
  author={Calvin Wu and Michael J. Econs and Linda A DiMeglio and Karl L. Insogna and Michael A Levine and P J Orchard and W P Miller and Anna Petryk and Eric T Rush and Dolores Marie Shoback and Leanne Marie Ward and Lynda E. Polgreen},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2017},
  volume={102 9},
  pages={
          3111-3123
        }
}
Background Osteopetrosis encompasses a group of rare metabolic bone diseases characterized by impaired osteoclast activity or development, resulting in high bone mineral density. Existing guidelines focus on treatment of the severe infantile forms with hematopoietic cell transplantation (HCT) but do not address the management of patients with less severe forms for whom HCT is not the standard of care. Therefore, our objective was to develop expert consensus guidelines for the management of… CONTINUE READING
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