Diagnosis, disease course, and management of patients with Kleine-Levin syndrome

  title={Diagnosis, disease course, and management of patients with Kleine-Levin syndrome},
  author={I. Arnulf and Thomas J Rico and E. Mignot},
  journal={The Lancet Neurology},
  • I. Arnulf, Thomas J Rico, E. Mignot
  • Published 2012
  • Psychology, Medicine
  • The Lancet Neurology
  • Kleine-Levin syndrome is a rare sleep disorder that mainly affects adolescents and is characterised by relapsing-remitting episodes of severe hypersomnia, cognitive impairment, apathy, derealisation, and psychiatric and behavioural disturbances. Boys are more frequently affected than girls. Just over half of patients have hyperphagia, are hypersexual (mainly boys), or have depressed mood (mainly girls), and 30% become anxious, delusional, and have hallucinations. Although some symptoms are… CONTINUE READING
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