Diagnosing and Treating Gout: A Review to Aid Primary Care Physicians

@article{Schlesinger2010DiagnosingAT,
  title={Diagnosing and Treating Gout: A Review to Aid Primary Care Physicians},
  author={Naomi Schlesinger},
  journal={Postgraduate Medicine},
  year={2010},
  volume={122},
  pages={157 - 161}
}
Abstract Generalist physicians, specifically general internists and primary care physicians, are often the first to see patients with gout and therefore play a critical role in the diagnosis and management of these patients. The aim of this review is to aid generalist physicians in diagnosing and treating gout. A case report example is presented to highlight some of the problems in diagnosing and treating gout. Practical practice points are also highlighted. 
Study on the diagnosis of gout with xanthine and hypoxanthine
TLDR
Xanthine and hypoxanthine, as precursors of uric acid, have been reported to be high in gout patients with hyperuricemia and presumed to be gout biomarkers.
A case of severe gout: A differential diagnosis
TLDR
It is possible to find chronic synovitis, bone erosion, and sometimes cartilage or tendon damage and it is mostly characterized by the presence of tophi3 composed of urate crystals piled up in soft tissue and joints.
Current Concepts in the Treatment of Gouty Arthritis
TLDR
A general overview of gouty arthritis including its pathophysiology, clinical presentations, diagnosis, predisposing factors and prophylactic therapy for preventing goutY arthritis flares is presented.
Clinical Manifestations and Diagnosis of Gout
Gout is one of the most common inflammatory arthritidies in men and postmenopausal women. It causes recurrent and severe pain in the affected joints, especially in the first metatarsophalangeal
Widespread gouty tophi on 18F-FDG PET/CT imaging.
TLDR
An F-FDG PET/CT was performed to evaluate the extent of a suspected gouty attack and to exclude any unexpected malignancy, and images showed multiple juxta-articular and subcutaneous foci of elevated F- FDG activity in both upper and lower extremities.
Role of individualized homoeopathic medicine in the treatment of gout - An observational study
TLDR
It was showed that homoeopathic treatment is very effective in reducing clinical symptoms and serum UA levels in subjects having gout.
Gout Prophylaxis Evaluated According to the 2012 American College of Rheumatology Guidelines: Analysis from the CORRONA Gout Registry
TLDR
Prophylaxis was significantly more common in patients with a higher disease burden and activity, which is in agreement with the ACR guidelines.
Current Management Concepts in Gouty Arthritis
TLDR
There is good evidence to support the treatment of gouty attacks by the timely, short-term use of non-steroidal anti-inflammatory drugs, colchicine, and glucocorticosteroids, and additional newer drugs such as IL-1 inhibitors have been developed to improve the management.
A large multilobulated ankle swelling: rare presentation of gout
TLDR
A male patient presented to outpatient department with large lobulated hard swelling in subcutaneous plane of left ankle with presence of uric acid crystals is presented, a very rare presentation of gout.
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