Diacyllipid micelle-based nanocarrier for magnetically guided delivery of drugs in photodynamic therapy.

@article{Cintez2006DiacyllipidMN,
  title={Diacyllipid micelle-based nanocarrier for magnetically guided delivery of drugs in photodynamic therapy.},
  author={Ludmila Otilia Cinteză and Tymish Y Ohulchanskyy and Yudhisthira Sahoo and Earl J. Bergey and Ravindra K Pandey and Paras N Prasad},
  journal={Molecular pharmaceutics},
  year={2006},
  volume={3 4},
  pages={415-23}
}
We report the design, synthesis using nanochemistry, and characterization of a novel multifunctional polymeric micelle-based nanocarrier system, which demonstrates combined function of magnetophoretically guided drug delivery together with light-activated photodynamic therapy. Specifically, the nanocarrier consists of polymeric micelles of diacylphospholipid-poly(ethylene glycol) (PE-PEG) coloaded with the photosensitizer drug 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a (HPPH), and… CONTINUE READING
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