Diabetic nephropathy induces alterations in the glomerular and tubule lipid profiles1[S]

@article{Grove2014DiabeticNI,
  title={Diabetic nephropathy induces alterations in the glomerular and tubule lipid profiles1[S]},
  author={Kerri J Grove and Paul A. Voziyan and Jeffrey M. Spraggins and Su-wan Wang and Paisit Paueksakon and Raymond C. Harris and Billy G. Hudson and Richard M. Caprioli},
  journal={Journal of Lipid Research},
  year={2014},
  volume={55},
  pages={1375 - 1385}
}
Diabetic nephropathy (DN) is a major life-threatening complication of diabetes. Renal lesions affect glomeruli and tubules, but the pathogenesis is not completely understood. Phospholipids and glycolipids are molecules that carry out multiple cell functions in health and disease, and their role in DN pathogenesis is unknown. We employed high spatial resolution MALDI imaging MS to determine lipid changes in kidneys of eNOS−/− db/db mice, a robust model of DN. Phospholipid and glycolipid… 

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