Diabetic ketoacidosis and hyperglycemic hyperosmolar state.

  title={Diabetic ketoacidosis and hyperglycemic hyperosmolar state.},
  author={Jelena Maletkovic and Andrew Jay Drexler},
  journal={Endocrinology and metabolism clinics of North America},
  volume={42 4},
Diabetic ketoacidosis (DKA) and the hyperglycemic hyperosmolar state (HHS) are potentially fatal hyperglycemic crises that occur as acute complications of uncontrolled diabetes mellitus. The authors provide a review of the current epidemiology, precipitating factors, pathogenesis, clinical presentation, evaluation, and treatment of DKA and HHS. The discovery of insulin in 1921 changed the life expectancy of patients with diabetes mellitus dramatically. Today, almost a century later, DKA and HHS… CONTINUE READING
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