Diabetic autonomic neuropathy and impaired human pancreatic polypeptide secretion in response to food.

@article{Lugari1987DiabeticAN,
  title={Diabetic autonomic neuropathy and impaired human pancreatic polypeptide secretion in response to food.},
  author={Roberta Lugari and Angelo Gnudi and P Dall'Argine and A Vattini and G Rignanese and B Dall'Aglio and Nazario Melchionda and Philip Colella and Andrea Luciani and Siro Toscani},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1987},
  volume={64 2},
  pages={279-82}
}
In normal subjects, the early human pancreatic polypeptide (hPP) increase induced by food is mainly dependent on vagal activity. Parasympathetic function and plasma hPP response to a standard mixed meal were evaluated in 10 long term insulin-dependent (type I) diabetic patients (group A), 6 age-matched newly diagnosed type I diabetic patients (group B), and 8 normal subjects. The indices of vagal function (beat to beat heart rate variation during deep breathing and the Valsalva maneuver) were… CONTINUE READING