Diabetic and idiopathic gastroparesis is associated with loss of CD206-positive macrophages in the gastric antrum.

@article{Grover2017DiabeticAI,
  title={Diabetic and idiopathic gastroparesis is associated with loss of CD206-positive macrophages in the gastric antrum.},
  author={Madhusudan Grover and Cheryl E Bernard and Pankaj Jay Pasricha and Henry P. Parkman and Simon J. Gibbons and James A Tonascia and Kenneth L. Koch and Richard W. McCallum and Irene Sarosiek and William L Hasler and Linda A. Nguyen and Thomas L. Abell and William J. Snape and Michael L. Kendrick and Todd Andrew Kellogg and Travis J Mckenzie and Frank A Hamilton and Gianrico Farrugia},
  journal={Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society},
  year={2017},
  volume={29 6}
}
BACKGROUND Animal studies have increasingly highlighted the role of macrophages in the development of delayed gastric emptying. However, their role in the pathophysiology of human gastroparesis is unclear. Our aim was to determine changes in macrophages and other cell types in the gastric antrum muscularis propria of patients with diabetic and idiopathic gastroparesis. METHODS Full thickness gastric antrum biopsies were obtained from patients enrolled in the Gastroparesis Clinical Research… CONTINUE READING
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