Diabetic Complications in Obese Type 2 Diabetic Rat Models

@inproceedings{Katsuda2014DiabeticCI,
  title={Diabetic Complications in Obese Type 2 Diabetic Rat Models},
  author={Yoshiaki Katsuda and Takeshi Ohta and Katsuhiro Miyajima and Yusuke Kemmochi and Tomohiko Sasase and Bin Tong and Masami Shinohara and Takahisa Yamada},
  booktitle={Experimental animals},
  year={2014}
}
We overviewed the pathophysiological features of diabetes and its complications in obese type 2 diabetic rat models: Otsuka Long-Evans Tokushima fatty (OLETF) rat, Wistar fatty rat, Zucker diabetic fatty (ZDF) rat and Spontaneously diabetic Torii (SDT) fatty rat. Pancreatic changes with progression of diabetes were classified into early changes, such as islet hypertrophy and degranulation of β cells, and degenerative changes, such as islet atrophy and fibrosis of islet with infiltration of… CONTINUE READING

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