Diabetes related cardiomyopathy time dependent echocardiographic evaluation in an experimental rat model.

@article{Mihm2001DiabetesRC,
  title={Diabetes related cardiomyopathy time dependent echocardiographic evaluation in an experimental rat model.},
  author={Michael J. Mihm and J. L. Seifert and Christen M Coyle and John Anthony Bauer},
  journal={Life sciences},
  year={2001},
  volume={69 5},
  pages={527-42}
}
Type I diabetes is associated with a unique form of cardiomyopathy in the absence of atherosclerosis. The mechanisms involved in this phenomenon are not defined, but in humans this is associated with initial diastolic dysfunction followed by altered contractile performance. A relevant animal model would provide opportunities for mechanistic studies and experimental therapeutics, but none have been previously established for this unique form of cardiac pathophysiology, particularly with respect… CONTINUE READING
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