Diabetes potentiates acetylcholine-induced relaxation in rabbit renal arteries.

@article{Alabad2001DiabetesPA,
  title={Diabetes potentiates acetylcholine-induced relaxation in rabbit renal arteries.},
  author={Jos{\'e} A. Alabad{\'i} and Francisco Javier Forcada Miranda and S{\'i}lvia Bartolom{\'e} Llorens and Rosa F Ruiz de Apodaca and Jos{\'e} Alberto Maroto Centeno and Enrique Alborch},
  journal={European journal of pharmacology},
  year={2001},
  volume={415 2-3},
  pages={
          225-32
        }
}
The response of rabbit renal arteries to acetylcholine and its endothelial modulation in diabetes were investigated. Acetylcholine induced concentration-related endothelium-dependent relaxation of renal arteries that was significantly more potent in diabetic rabbits than in control rabbits. Pretreatment with N(G)-nitro-L-arginine (L-NOArg), indomethacin, or L-NOArg plus indomethacin induced partial inhibition of acetylcholine-induced relaxation. Inhibition induced by L-NOArg plus indomethacin… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 11 CITATIONS

Experimental diabetes induces hyperreactivity of rabbit renal artery to 5-hydroxytryptamine.

  • European journal of pharmacology
  • 2002
VIEW 7 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 37 REFERENCES

Endothelial dysfunction in diabetes

A. S. De Vriese, T. J. Verbeuren, J. Van de Voorde, N. H. Lameire, P. M. Vanhoutte
  • Br. J. Pharmacol
  • 2000
VIEW 1 EXCERPT

Similar Papers

Loading similar papers…