Diabetes mellitus and thrombosis.

@article{Vazzana2012DiabetesMA,
  title={Diabetes mellitus and thrombosis.},
  author={Natale Vazzana and Paola Ranalli and Chiara Cuccurullo and Giovanni Dav{\'i}},
  journal={Thrombosis research},
  year={2012},
  volume={129 3},
  pages={
          371-7
        }
}
Atherothrombosis is the leading cause of morbidity and mortality in patients with diabetes mellitus. Several mechanisms contribute to the diabetic prothrombotic state, including endothelial dysfunction, coagulative activation and platelet hyper-reactivity. In particular, diabetic platelets are characterised by dysregulation of several signaling pathways leading to enhanced adhesion, activation and aggregation. These alterations result from the interaction among hyperglycemia, insulin resistance… CONTINUE READING

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