Diabetes mellitus and responses of the urinary bladder to acetylcholine: an in vitro study.

@article{Nsabimana2008DiabetesMA,
  title={Diabetes mellitus and responses of the urinary bladder to acetylcholine: an in vitro study.},
  author={Abdon M. Nsabimana and John A. O. Ojewole},
  journal={Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi},
  year={2008},
  volume={44 3-4},
  pages={143-50}
}
This study was prompted by the inconsistent reports and apparent controversies that exist in the biomedical literature on the responses of diabetic bladder strips to cholinergic nerve stimulation or exogenously-administered muscarinic agonists, especially acetylcholine (ACh). In the present study, acetylcholine-induced contractions of urinary bladders isolated from normoglycaemic (normal) and streptozotocin-treated, diabetic Wistar rats were examined under physiological conditions. Mechanical… CONTINUE READING