Diabetes mellitus, hypertension and medial temporal lobe atrophy: the LADIS study.

@article{Korf2007DiabetesMH,
  title={Diabetes mellitus, hypertension and medial temporal lobe atrophy: the LADIS study.},
  author={E. S. C. Korf and Elizabeth C W van Straaten and F-E. de Leeuw and Wiesje Maria van der Flier and Frederik Barkhof and Leonardo Pantoni and Anna Maria Basile and Domenico Inzitari and Timo Erkinjuntti and Lars-Olof Wahlund and Egill Rostrup and Reinhold Schmidt and Franz Fazekas and Philip Scheltens},
  journal={Diabetic medicine : a journal of the British Diabetic Association},
  year={2007},
  volume={24 2},
  pages={166-71}
}
HYPOTHESIS Based on recent findings on the association between vascular risk factors and hippocampal atrophy, we hypothesized that hypertension and diabetes mellitus (DM) are associated with medial temporal lobe atrophy (MTA) in subjects without disability, independent of the severity of white matter hyperintensities. METHODS In the Leukoaraiosis And DISability in the elderly (LADIS) study, we investigated the relationships between DM, hypertension, blood pressure and MTA in 582 subjects… CONTINUE READING

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