Diabetes in pregnancy: a review of current evidence

  title={Diabetes in pregnancy: a review of current evidence},
  author={Nisha Kapoor and Srividhya Sankaran and Steve L. Hyer and Hassan Shehata},
  journal={Current Opinion in Obstetrics and Gynecology},
Purpose of review There is controversy about the best approach to screening and management for gestational diabetes. In the recent Confidential Enquiry in Maternal and Child Health (CEMACH) the outcome of women with diabetes compared with women without diabetes. The results were exceptionally poor, suggesting the need for a new management approach. The aim of this review is to address these findings and our suggested care pathways. Recent findings The CEMACH report showed the congenital… Expand
Specialised fetal and maternal service: Outcome of pre-gestational diabetes
It was concluded that the presence of specialised maternal and fetal clinics reduces complications related to prenatal glycaemic control, however, complication related to preconception care remains high. Expand
Clinical presentation and management of diabetes mellitus in pregnancy
There was an increased rate of cesarean section in the study population, the incidences of maternal andPerinatal morbidity were low, and the perinatal outcomes were satisfactory. Expand
Outcome in gestational diabetes mellitus after various treatment modality: A tertiary center experience in North India
G gestational diabetes is a rising complication of pregnancy and if women receive proper medical nutritional therapy and insulin therapy during pregnancy, better maternal and fetal outcome could be achieved. Expand
Prevalence of gestational diabetes among pregnant women attending Erciyes University Medical Faculty.
The GDM prevalence at the obstetrics and gynecology department of the Erciyes University according to the Carpanter-Coustan and National Diabetes Data Group criteria was 11.4% and 6.2%, respectively. Expand
Gestational diabetes: risk factors and recent advances in its genetics and treatment
  • C. Petry
  • Medicine
  • British Journal of Nutrition
  • 2010
Recent advances and remaining gaps in knowledge about GDM are highlighted in terms of its genetics (where some of the recently discovered polymorphic risk Factors for type 2 diabetes have also proved to be risk factors for GDM) and its treatment by diet, exercise and drugs. Expand
A Clinical Study of Maternal Complications and Perinatal Outcomes in Diabetes Complicating Pregnancy
The objective of the study was to evaluate the maternal complications and perinatal outcomes in diabetes complicating pregnancy. It was a prospective cohort study performed in J S S Hospital MysoreExpand
Neonatal complications and risk factors among women with gestational diabetes mellitus
The higher risk of fetal malformations with GDM suggests that many of these women may have high glucose levels even during the first trimester, and policies and interventions regarding prenatal care should focus not only on how better diagnostic and treatment procedures can be implemented, but also on how they can reach older and migrant women as well as women of lower socioeconomic status. Expand
How often do we ask about pregnancy in the diabetes review clinic?
Electronic patient records of a target population of young women of child-bearing age with both type 1 and type 2 diabetes who were attending the diabetes review clinic over a period of three years from 2007 to 2010 are analysed to show failure to enquire and/or record the fertility intentions of young female patients with diabetes. Expand
Frequency of Gestational Diabetes Mellitus in Pregnant Women Referred to Alavi Hospital in Ardabil, 2017
Considering the increased frequency of GDM in this study in compare with previous studies, the higher rate of cesarean section among young women with diabetes, doing more studies are essential in future. Expand
Maternal Gestational Diabetes and Fetal Congenital Heart Disease: An Observational Study
Based on the data, women with GDM are considered to be at an increased risk of having a baby with CHD, due to a combination of hyperglycaemia, insulin resistance, an elevated BMI and more importantly, undiagnosed pre-gestational diabetes. Expand


Effect of treatment of gestational diabetes mellitus on pregnancy outcomes.
Treatment of gestational diabetes reduces serious perinatal morbidity and may also improve the woman's health-related quality of life. Expand
Authors response to: Use of insulin glargine during pregnancy: a case–control pilot study
  • N. Price, M. Gillmer
  • Medicine
  • BJOG : an international journal of obstetrics and gynaecology
  • 2007
The results of this pilot study indicate that insulin glargine treatment during pregnancy does not appear to be associated with increased fetal macrosomia or neonatal morbidity. Expand
Insulin-requiring diabetes in pregnancy: a randomized trial of active induction of labor and expectant management.
In women with uncomplicated insulin-requiring gestational or class B pregestational diabetes, expectant management of pregnancy after 38 weeks' gestation did not reduce the incidence of cesarean delivery and there was an increased prevalence of large-for-gestational-age infants. Expand
Use of insulin pumps in pregnancies complicated by type 2 diabetes and gestational diabetes in a multiethnic community.
Insulin pump therapy seems to be safe and effective for maintaining glycemic control in pregnancies complicated by GDM/type 2 diabetes and requiring large doses of insulin. Expand
Classification and Diagnosis of Diabetes Mellitus and Other Categories of Glucose Intolerance
  • Diabetes
  • 1979
A classification of diabetes and other categories of glucose intolerance, based on contemporary knowledge of this heterogeneous syndrome, was developed by an international workgroup sponsored by theExpand
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO Consultation
  • K. Alberti, P. Zimmet
  • Medicine
  • Diabetic medicine : a journal of the British Diabetic Association
  • 1998
A WHO Consultation has taken place in parallel with a report by an American Diabetes Association Expert Committee to re‐examine diagnostic criteria and classification of diabetes mellitus and is hoped that the new classification will allow better classification of individuals and lead to fewer therapeutic misjudgements. Expand
TRIPOD (TRoglitazone In the Prevention Of Diabetes): a randomized, placebo-controlled trial of troglitazone in women with prior gestational diabetes mellitus.
The unique two-phase study design of the TRIPOD trial will permit testing not only of the biological question about reversal of insulin resistance and prevention of diabetes, but also of the clinical question about whether early intervention is superior to late intervention. Expand
Antenatal care : routine care for the healthy pregnant woman
A version of this guideline for pregnant women, their partners and the public, called Routine antenatal care for healthy pregnant women. Understanding NICE guidance: information for pregnant women,Expand
Glucose tolerance of offspring of mother with gestational diabetes mellitus in a low‐risk population
The prevalence of impaired glucose tolerance and obesity in offspring of mothers whose pregnancies were complicated by gestational diabetes mellitus in a low‐risk population is described and the effect on outcomes of minimal intervention compared with tight control is investigated. Expand
A 10‐year retrospective analysis of pregnancy outcome in pregestational Type 2 diabetes: comparison of insulin and oral glucose‐lowering agents
To review the use of oral glucose‐lowering agents (OGLA) in pregnant women with Type 2 diabetes mellitus and to evaluate the effectiveness of these agents in relation to glucose control during pregnancy. Expand