Diabetes genes identified by genome-wide association studies are regulated in mice by nutritional factors in metabolically relevant tissues and by glucose concentrations in islets

@inproceedings{Ho2012DiabetesGI,
  title={Diabetes genes identified by genome-wide association studies are regulated in mice by nutritional factors in metabolically relevant tissues and by glucose concentrations in islets},
  author={Maggie M. Ho and Piriya Yoganathan and Kwan Yi Chu and Subashini Karunakaran and James D Johnson and Susanne M Clee},
  booktitle={BMC Genetics},
  year={2012}
}
BackgroundGenome-wide association studies (GWAS) have recently identified many new genetic variants associated with the development of type 2 diabetes. Many of these variants are in introns of known genes or between known genes, suggesting they affect the expression of these genes. The regulation of gene expression is often tissue and context dependent, for example occurring in response to dietary changes, hormone levels, or many other factors. Thus, to understand how these new genetic variants… CONTINUE READING
2
Twitter Mentions

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 93 REFERENCES