Diabetes changes the levels of ionotropic glutamate receptors in the rat retina

@inproceedings{Santiago2009DiabetesCT,
  title={Diabetes changes the levels of ionotropic glutamate receptors in the rat retina},
  author={Ana Raquel Santiago and Joana M. Gaspar and Filipa I Baptista and Armando J. Crist{\'o}v{\~a}o and Paulo J. Santos and Willem Kamphuis and Ant{\'o}nio Francisco Ambr{\'o}sio},
  booktitle={Molecular vision},
  year={2009}
}
PURPOSE Diabetic retinopathy (DR) is a leading cause of vision loss and blindness among adults between the age 20 to 74. Changes in ionotropic glutamate receptor subunit composition can affect retinal glutamatergic neurotransmission and, therefore, contribute to visual impairment. The purpose of this study was to investigate whether diabetes leads to changes in ionotropic glutamate receptor subunit expression at the protein and mRNA level in the rat retina. METHODS Changes in the expression… CONTINUE READING

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