Diabetes-associated complications in Spontaneously Diabetic Torii fatty rats.

  title={Diabetes-associated complications in Spontaneously Diabetic Torii fatty rats.},
  author={Kenichi Matsui and Takeshi Ohta and Tomohiro Oda and Tomohiko Sasase and Nobuhisa Ueda and Katsuhiro Miyajima and Taku Masuyama and Masami Shinohara and Mutsuyoshi Matsushita},
  journal={Experimental animals},
  volume={57 2},
The Spontaneously Diabetic Torii (SDT) fatty rat, established by introducing the fa allele of the Zucker fatty rat into the SDT rat genome, is a new model of obese type 2 diabetes. The SDT-fa/fa (SDT fatty) rat shows overt obesity, and hyperglycemia and hyperlipidemia are observed at a young age as compared with the SDT-+/+ (SDT normal) rat. However, the features of the diabetic complications in the SDT fatty rat have not been reported. In the present study, the incidence and the progression of… CONTINUE READING
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