Diabetes and semicarbazide-sensitive amine oxidase (SSAO) activity: a review.

  title={Diabetes and semicarbazide-sensitive amine oxidase (SSAO) activity: a review.},
  author={Toshio Obata},
  journal={Life sciences},
  volume={79 5},
The enzyme of semicarbazide-sensitive amine oxidase (SSAO) activity has been reported to be elevated in blood from diabetic patients. SSAO are widely distributed in plasma membranes of various tissues and blood plasma. SSAO-mediated production of toxic aldehydes has been proposed to be related to pathophysiological conditions. Cytotoxic metabolites by SSAO may cause endothelial injury and subsequently induce atherosclerosis. The precise physiological functions of SSAO could play an important… CONTINUE READING


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