Diabetes aggravates acute pancreatitis and inhibits pancreas regeneration in mice

@article{Zechner2012DiabetesAA,
  title={Diabetes aggravates acute pancreatitis and inhibits pancreas regeneration in mice},
  author={Dietmar Zechner and Marie Spitzner and Alexej Bobrowski and Niklas Knapp and Angela Kuhla and Brigitte Vollmar},
  journal={Diabetologia},
  year={2012},
  volume={55},
  pages={1526-1534}
}
Aims/hypothesisIt is well established that acute pancreatitis often causes diabetes and that a high blood glucose level associated with pancreatitis is a marker of poor prognosis. The aim of this study was to evaluate if diabetes merely reflects the severity of pancreatitis or whether it can also aggravate the progression of this disease in a vicious circle.MethodsReversible acute oedematous pancreatitis was induced in untreated and streptozotocin-treated diabetic mice by injection of cerulein… CONTINUE READING
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