• DOI:10.7326/M15-2650
Corpus ID: 32016657

Diabetes Medications as Monotherapy or Metformin-Based Combination Therapy for Type 2 Diabetes

@article{Maruthur2016DiabetesMA,
  title={Diabetes Medications as Monotherapy or Metformin-Based Combination Therapy for Type 2 Diabetes},
  author={Nisa M. Maruthur and E. Tseng and S. Hutfless and L. Wilson and Catalina Suarez-Cuervo and Zackary Berger and Y. Chu and E. Iyoha and J. Segal and S. Bolen},
  journal={Annals of Internal Medicine},
  year={2016},
  volume={164},
  pages={740-751}
}

Nisa M. Maruthur, E. Tseng, +7 authors S. Bolen

Published 2016

Medicine

Annals of Internal Medicine

Type 2 diabetes and its complications are a substantial public health burden, affecting 9.3% of the U.S. adult population (1, 2). Most patients with type 2 diabetes eventually require glucose-lowering pharmacologic therapy, with a goal of reducing long-term complications. More than 7 classes of diabetes medications, which differ in their effects on glucose-lowering, safety, and other important outcomes, are recommended as first- or second-line therapy (3, 4). The Agency for Healthcare Research… CONTINUE READING

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