Diabetes: Inhibit VEGF-B to treat T2DM?


Lipid accumulation in extra-adipose tissues and lipid-induced insulin resistance are strongly associated with the development of type 2 diabetes mellitus (T2DM). New findings in mice suggest that targeted inhibition of VEGF-B, which regulates endothelial uptake of fatty acids, could prevent lipid accumulation in extraadipose tissues and improve peripheral… (More)
DOI: 10.1038/nrendo.2012.195