Diabetes, cancer, and metformin: connections of metabolism and cell proliferation.

@article{Gallagher2011DiabetesCA,
  title={Diabetes, cancer, and metformin: connections of metabolism and cell proliferation.},
  author={Emily Jane Gallagher and Derek Leroith},
  journal={Annals of the New York Academy of Sciences},
  year={2011},
  volume={1243},
  pages={54-68}
}
Diabetes is associated with an increased risk of developing and dying from cancer. This increased risk may be due to hyperglycemia, hyperinsulinemia, and insulin resistance or other factors. Metformin has recently gained much attention as it appears to reduce cancer incidence and improve prognosis of patients with diabetes. In vitro data and animal studies support these findings from human epidemiological studies. Metformin has multiple potential mechanisms by which it inhibits cancer… CONTINUE READING