Di(2-thienyl)(3-quinuclidyl) carbinol (quiditene): An original antiulcerous drug of the quinuclidine series

Abstract

Systematic investigations into the synthesis and characterization of quinuclidine compounds, conducted at the Center for Drug Chemistry (Moscow) [1-3], revealed a highly promising class of compounds-diaryl(3-quinuclidyl)carbinols. This class contains original agents capable of blocking Hi-histamine receptors, of which the antiallergic drug phencarol (I) is already used in practice and the drug bicarphen (II) has been approved for medicinal application [ 4 6].

DOI: 10.1007/BF02641322

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Cite this paper

@article{Kaminka2007Di2thienyl3quinuclidylC, title={Di(2-thienyl)(3-quinuclidyl) carbinol (quiditene): An original antiulcerous drug of the quinuclidine series}, author={M. {\'e}. Kaminka and S. M. Tupikina and Natalia V Alekseeva and Leonid N Koikov and V. Ya. Vorob'eva and Anastasia Yanina and E. E. Mikhlina}, journal={Pharmaceutical Chemistry Journal}, year={2007}, volume={32}, pages={671-673} }