Di-(2 ethylhexyl) phthalate and flutamide alter gene expression in the testis of immature male rats

@article{Vo2009Di2EP,
  title={Di-(2 ethylhexyl) phthalate and flutamide alter gene expression in the testis of immature male rats},
  author={Thuy T B Vo and Eui-Man Jung and Vu Hoang Dang and Yeong-Min Yoo and Kyung-Chul Choi and Frank H Yu and Eui-Bae Jeung},
  journal={Reproductive Biology and Endocrinology : RB&E},
  year={2009},
  volume={7},
  pages={104 - 104}
}
We previously demonstrated that the androgenic and anti-androgenic effects of endocrine disruptors (EDs) alter reproductive function and exert distinct effects on developing male reproductive organs. To further investigate these effects, we used an immature rat model to examine the effects of di-(2 ethylhexyl) phthalate (DEHP) and flutamide (Flu) on the male reproductive system. Immature male SD rats were treated daily with DEHP and Flu on postnatal days (PNDs) 21 to 35, in a dose-dependent… CONTINUE READING
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