Dextromethorphan and codeine: objective assessment of antitussive activity in patients with chronic cough.

@article{Matthys1983DextromethorphanAC,
  title={Dextromethorphan and codeine: objective assessment of antitussive activity in patients with chronic cough.},
  author={Heinrich Matthys and B K Bleicher and U Bleicher},
  journal={The Journal of international medical research},
  year={1983},
  volume={11 2},
  pages={92-100}
}
Dextromethorphan, the most widely used cough suppressant in the U.S.A., was compared with codeine, the traditional European antitussive, in a double-blind, crossover trial using both an objective and subjective assessment of efficacy in sixteen patients with chronic, stable cough. Both preparations, at a dose of 20 mg, were similarly effective in reducing cough frequency. Dextromethorphan lowered cough intensity to a greater degree than codeine (p less than 0.0008) and was considered the better… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

Important drugs for cough in advanced cancer

Supportive Care in Cancer • 2001
View 13 Excerpts
Highly Influenced

Antitussive drugs--past, present, and future.

Pharmacological reviews • 2014
View 4 Excerpts
Highly Influenced

Current drugs for the treatment of dry cough.

The Journal of the Association of Physicians of India • 2013

Similar Papers

Loading similar papers…