Dextromethorphan Plus Ultra Low‐Dose Quinidine Reduces Pseudobulbar Affect

  title={Dextromethorphan Plus Ultra Low‐Dose Quinidine Reduces Pseudobulbar Affect},
  author={E. Pioro and B. Brooks and J. Cummings and R. Schiffer and R. Thisted and D. Wynn and A. Hepner and R. Kaye},
  journal={Annals of Neurology},
  • E. Pioro, B. Brooks, +5 authors R. Kaye
  • Published 2010
  • Medicine
  • Annals of Neurology
  • To evaluate dextromethorphan combined with ultra low‐dose quinidine (DMq) for treating pseudobulbar affect (PBA) in patients with amyotrophic lateral sclerosis (ALS) or multiple sclerosis (MS). 
    143 Citations

    Paper Mentions

    Interventional Clinical Trial
    The primary objective of this study is to test the hypothesis that Nuedexta (20/10) administered orally will reduce Pseudobulbar Affect (PBA) frequency and severity (CNS-Lability… Expand
    ConditionsAlzheimer's Disease, Pseudobulbar Affect (PBA)
    Interventional Clinical Trial
    Objectives of the study are to evaluate the safety, tolerability, and efficacy of two different doses of AVP-923 (capsules containing either 30 mg of dextromethorphan hydrobromide… Expand
    ConditionsPseudobulbar Affect (PBA)
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