Dextran-based hydrogel formed by thiol-Michael addition reaction for 3D cell encapsulation.

@article{Liu2015DextranbasedHF,
  title={Dextran-based hydrogel formed by thiol-Michael addition reaction for 3D cell encapsulation.},
  author={Zhen Liu and Zhao Wei and Xv Long Zhu and Guo You Huang and Feng Xu and Jian Yang and Yoshihito Osada and Mikl{\'o}s Zr{\'i}nyi and Jian Li and Yong Mei Chen},
  journal={Colloids and surfaces. B, Biointerfaces},
  year={2015},
  volume={128},
  pages={140-8}
}
Cell encapsulation in three-dimensional (3D) hydrogels can mimic native cell microenvironment and plays a major role in cell-based transplantation therapies. In this contribution, a novel in situ-forming hydrogel, Dex-l-DTT hydrogel ("l" means "linked-by"), by cross-linking glycidyl methacrylate derivatized dextran (Dex-GMA) and dithiothreitol (DTT) under physiological conditions, has been developed using thiol-Michael addition reaction. The mechanical properties, gelation process and degree of… CONTINUE READING