Dextran Sulfate Sodium-Induced Colitis in Immunodeficient Rats

Abstract

To examine the morphology of colitis and study the role of the immune system in colitis, we compared colitis in immunocompetent Wistar-Kyoto rats with that in spontaneously hypertensive rats, known to have T-cell dysfunction. Rats were treated with 3% dextran sulfate in drinking water for periods ranging from 3 to 60 days. Diarrhea developed earlier and was… (More)
DOI: 10.1023/A:1005678606273

7 Figures and Tables

Topics

  • Presentations referencing similar topics