Dexmedetomidine with magnesium sulphate as adjuvants in caudal block to augment anaesthesia and analgesia in paediatric lower abdominal surgeries

@article{Sayed2018DexmedetomidineWM,
  title={Dexmedetomidine with magnesium sulphate as adjuvants in caudal block to augment anaesthesia and analgesia in paediatric lower abdominal surgeries},
  author={J. Sayed and E. Kamel and M. Riad and S. Abd-Elshafy and R. Hanna},
  journal={Egyptian Journal of Anaesthesia},
  year={2018},
  volume={34},
  pages={114 - 122}
}
Abstract Purpose To investigate the implication of dexmedetomidine and magnesium sulphate addition to bupivacaine in caudal anesthesia in paediatric lower abdominal surgeries. Study design Randomized controlled trial. Setting Paediatric University Hospital. Subjects 120 children undergoing surgeries in the lower half of the body under general anaesthesia with a supplementary caudal block using 1 ml/kg bupivacaine 0.25%. Methods Participants were randomly allocated into four groups; group C… Expand
1 Citations
Efficacy and safety of caudal dexmedetomidine in pediatric infra-umbilical surgery: a meta-analysis and trial-sequential analysis of randomized controlled trials
TLDR
The results suggest that the addition of dexmedetomidine to local anesthetic in caudal block significantly improves the duration of analgesia and reduces the analgesic requirements, while maintaining a similar risk-profile compared with local anesthetics alone. Expand

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Caudal dexmedetomidine with 0.25% ropivacaine for paediatric lower abdominal surgeries achieved significant postoperative pain relief that resulted in a better quality of sleep and a prolonged duration of arousable sedation and produced less incidence of emergence agitation following sevoflurane anaesthesia. Expand
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