Dexmedetomidine alleviates anxiety-like behaviors and cognitive impairments in a rat model of post-traumatic stress disorder

@article{Ji2014DexmedetomidineAA,
  title={Dexmedetomidine alleviates anxiety-like behaviors and cognitive impairments in a rat model of post-traumatic stress disorder},
  author={M. H. Ji and Min Jia and Ming-qiang Zhang and Wen-Xue Liu and Jian-jun Yang},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2014},
  volume={54},
  pages={284-288}
}
Post-traumatic stress disorder (PTSD) is a psychiatric disease that has substantial health implications, including high rates of health morbidity and mortality, as well as increased health-related costs. Although many pharmacological agents have proven the effects on the development of PTSD, current pharmacotherapies typically only produce partial improvement of PTSD symptoms. Dexmedetomidine is a selective, short-acting α2-adrenoceptor agonist, which has anxiolytic, sedative, and analgesic… CONTINUE READING

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National Natural Science Foundation of China (Nos. 81271216 and 81300946) and the Natural Science Foundation of Jiangsu Province (No. BK2012778)

  • JK Boehnlein, JD Kinzie
  • 2012

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