Dexlansoprazole: A proton pump inhibitor with a dual delayed-release system.
@article{Emerson2010DexlansoprazoleAP, title={Dexlansoprazole: A proton pump inhibitor with a dual delayed-release system.}, author={Christopher R. Emerson and Nino Marzella}, journal={Clinical therapeutics}, year={2010}, volume={32 9}, pages={ 1578-96 } }
BACKGROUND
Dexlansoprazole, the dextrorotatory enantiomer of lansoprazole, is a proton pump inhibitor (PPI) formulated to have dual delayed-release properties. It is indicated for healing all grades of esophagitis, maintaining the healing of erosive esophagitis (EE), and treating heartburn associated with nonerosive gastroesophageal reflux disease.
OBJECTIVE
This article reviews the pharmacology, pharmacokinetics, and pharmacodynamics of dexlansoprazole, as well as its clinical efficacy and… Expand
19 Citations
Development of Dexlansoprazole Delayed-Release Capsules, a Dual Delayed-Release Proton Pump Inhibitor.
- Chemistry, Medicine
- Journal of pharmaceutical sciences
- 2019
- 2
Dexlansoprazole: delayed-release orally disintegrating tablets for the treatment of heartburn associated with non-erosive gastroesophageal reflux disease and the maintenance of erosive esophagitis
- Medicine
- Expert review of gastroenterology & hepatology
- 2016
- 6
- Highly Influenced
Need of Combining Proton Pump Inhibitors with Prokinetics: A Prospective Observational Survey Conducted in India
- Medicine
- 2018
- 1
- PDF
Stereoselective and nonstereoselective pharmacokinetics of rabeprazole – an overview
- Chemistry, Medicine
- Xenobiotica; the fate of foreign compounds in biological systems
- 2018
- 5
Potassium-competitive acid blockers: Advanced therapeutic option for acid-related diseases.
- Medicine
- Pharmacology & therapeutics
- 2016
- 38
High and Frequent Dose of Dexlansoprazole and Amoxicillin Dual Therapy for Helicobacter pylori Infections: A Single Arm Prospective Study.
- Medicine
- The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
- 2017
- 9
- PDF
Current Pharmacological Management of Gastroesophageal Reflux Disease
- Medicine
- Gastroenterology research and practice
- 2013
- 31
- PDF
Bioavailability of dexlansoprazole delayed-release capsule granules when administered via nasogastric tube or orally via syringe
- Medicine
- Clinical and experimental gastroenterology
- 2018
- PDF
References
SHOWING 1-10 OF 54 REFERENCES
Drug Interaction Studies with Dexlansoprazole Modified Release (TAK-390MR), a Proton Pump Inhibitor with a Dual Delayed-Release Formulation
- Medicine
- Clinical Drug Investigation
- 2009
- 29
- PDF
Effects of Dexlansoprazole MR, a Novel Dual Delayed Release Formulation of a Proton Pump Inhibitor, on Plasma Gastrin Levels in Healthy Subjects
- Medicine
- Journal of clinical pharmacology
- 2009
- 13
Effectiveness of proton pump inhibitors in nonerosive reflux disease.
- Medicine
- Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
- 2004
- 398
Gastric acid control with esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole: a five-way crossover study
- Medicine
- American Journal of Gastroenterology
- 2003
- 358
- PDF
Efficacy and safety of esomeprazole compared with omeprazole in GERD patients with erosive esophagitis: a randomized controlled trial
- Medicine
- American Journal of Gastroenterology
- 2001
- 381
Review article: dual delayed release formulation of dexlansoprazole MR, a novel approach to overcome the limitations of conventional single release proton pump inhibitor therapy
- Medicine
- Alimentary pharmacology & therapeutics
- 2009
- 109
- PDF
Esomeprazole (40 mg) compared with lansoprazole (30 mg) in the treatment of erosive esophagitis
- Medicine
- American Journal of Gastroenterology
- 2002
- 429
Lack of Electrocardiographic Effect of Dexlansoprazole MR, a Novel Modified‐Release Formulation of the Proton Pump Inhibitor Dexlansoprazole, in Healthy Participants
- Medicine
- Journal of clinical pharmacology
- 2009
- 8
Medical treatments for the maintenance therapy of reflux oesophagitis and endoscopic negative reflux disease.
- Medicine
- The Cochrane database of systematic reviews
- 2005
- 186
- PDF
Review article: the unmet needs in delayed‐release proton‐pump inhibitor therapy in 2005
- Medicine
- Alimentary pharmacology & therapeutics
- 2005
- 51