Dexamethasone uptake in the murine organ of Corti with transtympanic versus systemic administration

OBJECTIVE To investigate glucocorticoid uptake in auditory hair cells following transtympanic versus systemic administration of dexamethasone. STUDY DESIGN Controlled experimental study. SETTING Translational science experimental laboratory. METHODS Swiss-Webster mice were injected with dexamethasone via transtympanic or systemic administration. At 1… CONTINUE READING

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