Dexamethasone suppresses mucus production and MUC-2 and MUC-5AC gene expression by NCI-H292 cells.

@article{Kai1996DexamethasoneSM,
  title={Dexamethasone suppresses mucus production and MUC-2 and MUC-5AC gene expression by NCI-H292 cells.},
  author={Hirofumi Kai and Kazusada Yoshitake and Akinobu Hisatsune and Tadashi Kido and Yoichiro Isohama and Kazuo Takahama and Takeshi Miyata},
  journal={The American journal of physiology},
  year={1996},
  volume={271 3 Pt 1},
  pages={L484-8}
}
Excessive production of airway mucus is a characteristic feature of many chronic inflammatory lung diseases. Although current pharmacological approaches to excessive mucus production are limited, glucocorticoids appear to be the most effective among a few useful drugs. The exact evidence for the effectiveness of glucocorticoids on mucus production has not been fully elucidated to date. The purpose of this study is to clarify the effect of dexamethasone on mucus production and mucin gene… CONTINUE READING

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