Dexamethasone reverses TGF‐β‐mediated inhibition of primary rat preadipocyte differentiation

@article{Shin2003DexamethasoneRT,
  title={Dexamethasone reverses TGF‐$\beta$‐mediated inhibition of primary rat preadipocyte differentiation},
  author={S. Shin and Kun-Yong Kim and J. K. Kim and S. Yoon and I. Choi and Young Yang},
  journal={FEBS Letters},
  year={2003},
  volume={543}
}
Dexamethasone and transforming growth factor‐β (TGF‐β) show contrary effects on differentiation of adipocytes. Dexamethasone stimulates adipocyte differentiation whereas TGF‐β inhibits it. In the present study, we investigated whether dexamethasone could reverse the TGF‐β‐mediated inhibition of preadipocyte differentiation. Primary rat preadipocytes, obtained from Sprague–Dawley rats, were pretreated with dexamethasone in the presence or absence of TGF‐β, prior to the induction of… Expand
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