Dexamethasone reduces gut permeability in pediatric cardiac surgery.

  title={Dexamethasone reduces gut permeability in pediatric cardiac surgery.},
  author={Ignacio Malagon and Willem Onkenhout and Margreet Klok and Lisa Linthorst and Petrus F H van der Poel and James G. Bovill and Mark Gerard Hazekamp},
  journal={The Journal of thoracic and cardiovascular surgery},
  volume={130 2},
OBJECTIVES Little attention has been paid to the effect of the systemic inflammatory response syndrome on intestinal dysfunction in the postoperative period. Several proinflammatory cytokines have been reported to increase the permeability of intestinal mucosa in vitro. We investigated the effect of dexamethasone on gut permeability in pediatric patients undergoing cardiac surgery by using the dual sugar permeability test and absorption of 2 other saccharides. METHODS Thirty-four patients… CONTINUE READING