Dexamethasone prophylaxis before thyroidectomy to reduce postoperative nausea, pain, and vocal dysfunction: A randomized clinical controlled trial

@article{Feroci2011DexamethasonePB,
  title={Dexamethasone prophylaxis before thyroidectomy to reduce postoperative nausea, pain, and vocal dysfunction: A randomized clinical controlled trial},
  author={Francesco Feroci and Marco Rettori and Andrea Borrelli and Elisa Lenzi and Alessandra Ottaviano and Marco Scatizzi},
  journal={Head \& Neck},
  year={2011},
  volume={33}
}
The objective of this 2‐arm, double‐blind, randomized, controlled study was to assess the effects of a preoperative single dose steroid on postoperative nausea and vomiting (PONV), pain, and vocal function after thyroidectomy for benign disease. 
Effect of Palonosetron, Dexamethasone, or Palonosetron and Dexamethasone in Postoperative Nausea and Vomiting in Highly Susceptible Thyroidectomy Patients: A Randomized Trial
Our study aimed to compare the efficacy of dexamethasone added to palonosetron to both palonosetron and dexamethasone monotherapy for preventing postoperative nausea and vomiting in highly suscepti...
Efficacy of a Single Preoperative Dexamethasone Dose to Prevent Nausea and Vomiting After Thyroidectomy (the tPONV Study): A Randomized, Double-blind, Placebo-controlled Clinical Trial
TLDR
A single dose of preoperative dexamethasone administration is an effective, safe, and economical measure to reduce PONV incidence after thyroidectomy.
Dexamethasone Reduces Nausea and Vomiting but not Pain after Thyroid Surgery: A Meta-Analysis of Randomized Controlled Trials
  • B. Li, Hui-xia Wang
  • Medicine
    Medical science monitor : international medical journal of experimental and clinical research
  • 2014
TLDR
A single preoperative administration of dexamethasone reduced the incidence and severity of PONV but not pain severity and analgesic consumption in patients undergoing thyroidectomy.
Dexamethasone for Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Thyroidectomy: Meta-analysis of Randomized Controlled Trials
TLDR
A single preoperative administration of dexamethasone reduced the incidence of PONV and analgesic requirements in patients undergoing thyroidectomy and should be considered for routine clinical practice.
Role of Prophylactic Dexamethasone Before Thyroidectomy in Reducing Postoperative Pain, Nausea and Vomiting
TLDR
A single dose of prophylactic dexamethasone significantly reduces the mean pain score in patients undergoing thyroidectomy; however, insignificant relation was noted in terms of PONV condition.
Use of Prophylactic Steroids to Prevent Hypocalcemia and Voice Dysfunction in Patients Undergoing Thyroidectomy: A Randomized Clinical Trial.
TLDR
A single preoperative dose of dexamethasone was safe and effective in reducing postoperative hypocalcemia and voice dysfunction rates in patients undergoing thyroidectomy.
Dexamethazone Prophylaxis before Near Total Thyroidectomy to Reduce Vocal Dysfunction: A Randomized Clinical Trial
TLDR
It was shown that dexamethasone 8 mg/2ml IV before near total thyroidectomy has significant effect regarding reduction of postoperative nausea, pain, vomiting, hypocalcaemia and vocal cords mobility, which was less affected.
Adverse side effects of dexamethasone in surgical patients.
TLDR
The effects of a steroid load of dexamethasone on postoperative systemic or wound infection, delayed wound healing, and blood glucose change in adult surgical patients (with planned subgroup analysis of patients with and without diabetes).
Adverse side effects of dexamethasone in surgical patients.
TLDR
The effects of a steroid load of dexamethasone on postoperative systemic or wound infection, delayed wound healing, and blood glucose change in adult surgical patients with and without diabetes is assessed.
Adverse side effects of dexamethasone in surgical patients
TLDR
A single dose of dexamethasone probably does not increase the risk for postoperative infection and may produce a mild increase in glucose levels among participants without diabetes during the first 12 hours after surgery, which suggests a mild effect on delayed wound healing in the general surgical population.
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References

SHOWING 1-10 OF 56 REFERENCES
The Prophylactic Effect of Dexamethasone on Postoperative Nausea and Vomiting in Women Undergoing Thyroidectomy
The aim of this study was to evaluate the prophylactic effect of dexamethasone on postoperative nausea and vomiting (PONV) in women undergoing thyroidectomy.Droperidol and saline served as controls.
Use of intravenous steroids at induction of anaesthesia for adult tonsillectomy to reduce post‐operative nausea and vomiting and pain: a double‐blind randomized controlled trial
  • S. Mckean, X. Kochilas, R. Kelleher, M. Dockery
  • Medicine
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
  • 2006
Objective:  To assess the effectiveness of intravenous steroids at induction of anaesthetic to reduce post‐operative nausea and vomiting and pain after adult tonsillectomy.
Randomized Controlled Trial on Single Dose Steroid Before Thyroidectomy for Benign Disease to Improve Postoperative Nausea, Pain, and Vocal Function
TLDR
A preoperative single dose of steroid significantly reduced nausea, vomiting, and pain, and improved postoperative voice function within the first 48 hours (most pronounced within 16 hours) after thyroid resection; this strategy should be routinely applied in thyroidectomies.
The Effects of Preoperative Steroids on Tonsillectomy Patients
TLDR
A prospective, randomized, doubleblind study to determine the postoperative efficacy of steroids in tonsillectomy was performed and there were no statistical differences noted in any of the variables compared in the two groups.
[Postoperative nausea and vomiting].
TLDR
A rational approach to postoperative nausea and vomiting is proposed and the scoring of patients at risk, rational anaesthetic agents, prophylactic administration of antiemetics to patients atrisk and effective postoperative antiemetic treatment are suggested.
Prevention of Postoperative Nausea and Vomiting after Thyroidectomy
TLDR
The prophylactic combination of antiemetic treatment with dexamethasone and ginger was not clinically or statistically superior to dexamETHasone alone in preventing PONV in patients undergoing thyroidectomy.
The prophylactic effect of dexamethasone on postoperative nausea and vomiting in women undergoing thyroidectomy: a comparison of droperidol with saline.
TLDR
It is concluded that, although both dexamethasone and droperidol are effective as prophylactic antiemetics in women undergoing thyroidectomy, droperinidol produces more side effects, which suggests that dexamETHasone is a useful treatment in these patients.
The Use of Dexamethasone for Preventing Postoperative Nausea and Vomiting in Females Undergoing Thyroidectomy: A Dose-Ranging Study
We sought to determine the minimum effective dose of dexamethasone in preventing postoperative nausea and vomiting in women undergoing thyroidectomy. Two hundred twenty-five women (n = 45 in each of
Combination of ondansetron and dexamethasone in the prophylaxis of postoperative nausea and vomiting.
TLDR
Prophylactic administration of combined ondansetron and dexamethasone is effective in preventing postoperative nausea and vomiting in ASA I-II females undergoing general anaesthesia for major gynaecological surgery.
Efficacy of dexamethasone for reducing postoperative nausea and vomiting and analgesic requirements after thyroidectomy
  • Y. Fujii, M. Nakayama
  • Medicine
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • 2007
...
1
2
3
4
5
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