Dexamethasone prevents granulocyte-macrophage colony-stimulating factor-induced nuclear factor-kappaB activation, inducible nitric oxide synthase expression and nitric oxide production in a skin dendritic cell line.

Abstract

AIMS Nitric oxide (NO) has been increasingly implicated in inflammatory skin diseases, namely in allergic contact dermatitis. In this work, we investigated the effect of dexamethasone on NO production induced by the epidermal cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) in a mouse fetal skin dendritic cell line. METHODS NO production… (More)

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@article{Vital2003DexamethasonePG, title={Dexamethasone prevents granulocyte-macrophage colony-stimulating factor-induced nuclear factor-kappaB activation, inducible nitric oxide synthase expression and nitric oxide production in a skin dendritic cell line.}, author={Ana Lu{\'i}sa Vital and Margarida Gonçalo and Maria Teresa Cruz and Am{\'e}rico Manuel Da Costa Figueiredo and Carlos Bandeira Duarte and Mar{\'i}a Celeste Lopes}, journal={Mediators of Inflammation}, year={2003}, volume={12}, pages={71 - 78} }