Dexamethasone palmitate successfully attenuates hemophagocytic syndrome after allogeneic stem cell transplantation: macrophage-targeted steroid therapy.

Abstract

Hemophagocytic syndrome (HPS) induced by uncontrolled macrophage activation and subsequent graft failure is a frequent and prominent complication after allogeneic stem cell transplantation (allo-SCT), a cause of severe morbidity and death, and a therapeutic challenge. Liposome-incorporated dexamethasone, dexamethasone palmitate (DP), shows greater efficacy… (More)
DOI: 10.1007/s12185-012-1023-z

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@article{Nishiwaki2012DexamethasonePS, title={Dexamethasone palmitate successfully attenuates hemophagocytic syndrome after allogeneic stem cell transplantation: macrophage-targeted steroid therapy.}, author={Satoshi Nishiwaki and Takayuki Nakayama and Makoto Murata and Tetsuya Nishida and Kyoko Sugimoto and Shigeki Saito and Tomonori Kato and Hiroki Mizuno and Nobuhiko Imahashi and Aika Seto and Yukiyasu Ozawa and Tatsunori Goto and Daisuke Koyama and Emi Yokohata and Naomi Kubota and Sonoko Kamoshita and Koichi Miyamura and Kimikazu Matsumoto and Masafumi Ito and Tomoki Naoe}, journal={International journal of hematology}, year={2012}, volume={95 4}, pages={428-33} }