Dexamethasone induces the GLUT4 glucose transporter, and responses of glucose transport to norepinephrine and insulin in primary cultures of brown adipocytes.

@article{Shimizu1994DexamethasoneIT,
  title={Dexamethasone induces the GLUT4 glucose transporter, and responses of glucose transport to norepinephrine and insulin in primary cultures of brown adipocytes.},
  author={Yuki Shimizu and Dana M Kielar and Hiroshi Masuno and Yasuhiko Minokoshi and Takashi Shimazu},
  journal={Journal of biochemistry},
  year={1994},
  volume={115 6},
  pages={1069-74}
}
Glucose uptake into brown adipose tissue is enhanced directly by norepinephrine released from the sympathetic nerves. In the present study, we tried to establish culture conditions for brown adipocytes which are favorable for investigation of this unique glucose transport. Stromal-vascular cells isolated from the interscapular brown adipose tissue of newborn rats differentiated into brown adipocytes expressing the uncoupling protein, when the cells were maintained on collagen-coated dishes… CONTINUE READING

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