Dexamethasone induces rapid actin assembly in human endometrial cells without affecting its synthesis.

@article{Koukouritaki1997DexamethasoneIR,
  title={Dexamethasone induces rapid actin assembly in human endometrial cells without affecting its synthesis.},
  author={S B Koukouritaki and Andrew N. Margioris and Achilleas Gravanis and Roland Hartig and Christos Stournaras},
  journal={Journal of cellular biochemistry},
  year={1997},
  volume={65 4},
  pages={492-500}
}
Dexamethasone exerts a stimulatory effect of rapid-onset on the polymerization of actin. This has been documented in human endometrial adenocarcinoma Ishikawa cells, resulting in an acute, dose-dependent decrease in the G/total-actin ratio. In the present study we completely characterized this fast and apparently nongenomic effect of dexamethasone on actin assembly. We followed the morphological alterations of actin cytoskeleton and measured the time-dependent dynamics of actin polymerization… CONTINUE READING