Dexamethasone-induced and estradiol-induced CREB activation and annexin 1 expression in CCRF-CEM lymphoblastic cells: evidence for the involvement of cAMP and p38 MAPK.

@article{CastroCaldas2003DexamethasoneinducedAE,
  title={Dexamethasone-induced and estradiol-induced CREB activation and annexin 1 expression in CCRF-CEM lymphoblastic cells: evidence for the involvement of cAMP and p38 MAPK.},
  author={Margarida Castro-Caldas and Alexandrina Ferreira Mendes and Carlos B Duarte and Marcelo Fernandes Lopes},
  journal={Mediators of Inflammation},
  year={2003},
  volume={12},
  pages={329 - 337}
}
AIMS Annexin 1 (ANXA1), a member of the annexin family of calcium-binding and phospholipid-binding proteins, is a key mediator of the anti-inflammatory actions of steroid hormones. We have previously demonstrated that, in the human lymphoblastic CCRF-CEM cell line, both the synthetic glucocorticoid hormone, dexamethasone (Dex), and the estrogen hormone, 17beta-estradiol (E2beta), induce the synthesis of ANXA1, by a mechanism independent of the activation of their nuclear receptors. Recently, it… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 11 CITATIONS

Molecular mechanisms of hormonal and hormonal-cytokine control of immune tolerance in pregnancy

  • Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology
  • 2014
VIEW 1 EXCERPT
CITES BACKGROUND

Anti-Inflammatory Agents for Cancer Therapy.

  • Molecular and cellular pharmacology
  • 2009
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 60 REFERENCES

Dexamethasone induces the secretion of annexin I in immature lymphoblastic cells by a calcium-dependent mechanism

M. Castro-Caldas, C. B. Duarte, A. P. Carvalho, M. C. Fernandes Lopes
  • Molecular and Cellular Biochemistry
  • 2002
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Basic fibroblast growth factor upregulates cyclooxigenase-2 in 1407 cells through p38 MAP kinase

TG Tessner, F Muhale, +3 authors WF. Atenson
  • Am J Physiol Gastrointest Liver Physiol
  • 2003

Similar Papers

Loading similar papers…