Dexamethasone increases pigment epithelium-derived factor in perfused human eyes.

Abstract

PURPOSE To investigate the effects of dexamethasone (DEX) on pigment epithelium-derived factor (PEDF) cDNA and secreted protein in human trabecular meshwork (TM). METHODS Anterior segment organ cultures were perfused with 0.1 microM DEX (OD) and vehicle (OS). Primary human TM cells (HTM) were treated with DEX under similar conditions. PEDF mRNA and… (More)
DOI: 10.1080/02713680802110208

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