Dexamethasone effects on beta-adrenergic receptors and adenylate cyclase regulatory proteins Gs and Gi in ROS 17/2.8 cells.

@article{Rodan1986DexamethasoneEO,
  title={Dexamethasone effects on beta-adrenergic receptors and adenylate cyclase regulatory proteins Gs and Gi in ROS 17/2.8 cells.},
  author={Sevgi B. Rodan and Gideon A. Rodan},
  journal={Endocrinology},
  year={1986},
  volume={118 6},
  pages={2510-8}
}
Treatment of ROS 17/2.8 cells with dexamethasone (dex) increases (-)isoproterenol (ISO)-, PTH-, cholera toxin-, guanine nucleotide-, NaF-, and forskolin-stimulated adenylate cyclase activity. Enhanced hormone stimulation was first apparent 12 h after dex addition. (-)-[3H]Dihydroalprenolol binding, displaceable by ISO, increased up to 2-fold in dex-treated cells. This effect depended on protein synthesis and closely paralleled the extent and time course of the increase in adenylate cyclase… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Effects of beta-blockers on fracture risk.

Journal of musculoskeletal & neuronal interactions • 2008
View 1 Excerpt

Mechanisms of regulation of G(11)alpha protein by dexamethasone in osteoblastic UMR 106-01 cells.

American journal of physiology. Endocrinology and metabolism • 2002
View 1 Excerpt

Similar Papers

Loading similar papers…