Dexamethasone and epinephrine stimulate surfactant secretion in type II cells of embryonic chickens.

  title={Dexamethasone and epinephrine stimulate surfactant secretion in type II cells of embryonic chickens.},
  author={Lucy Catherine Sullivan and Sandra Orgeig},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  volume={281 3},
  • L. SullivanS. Orgeig
  • Published 1 September 2001
  • Biology
  • American journal of physiology. Regulatory, integrative and comparative physiology
Pulmonary surfactant (PS), a mixture of phospholipids and proteins secreted by alveolar type II cells, functions to reduce the surface tension in the lungs of all air-breathing vertebrates. Here we examine the control of PS during lung development in a homeothermic egg-laying vertebrate. In mammals, glucocorticoids and autonomic neurotransmitters contribute to the maturation of the surfactant system. We examined whether dexamethasone, epinephrine, and carbamylcholine hydrochloride (agonist for… 

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