Dex/CRH test cortisol response in outpatients with major depression and matched healthy controls

@article{Carpenter2009DexCRHTC,
  title={Dex/CRH test cortisol response in outpatients with major depression and matched healthy controls},
  author={Linda L Carpenter and Nicole S. Ross and Audrey R. Tyrka and George M. Anderson and Lawrence H Price},
  journal={Psychoneuroendocrinology},
  year={2009},
  volume={34},
  pages={1208-1213}
}
BACKGROUND The dexamethasone/corticotropin releasing hormone (Dex/CRH) test has been proposed as a potential tool for identifying endophenotypes relevant to mood disorders. An exaggerated cortisol response to the test during major depressive episodes has been demonstrated for inpatients with melancholic or psychotic features. A diminished hormone response has been observed in chronically depressed outpatients. METHODS Following a battery of self-report and interview assessments, 68 adults… CONTINUE READING

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