Deviant white matter structure in adults with attention-deficit/hyperactivity disorder points to aberrant myelination and affects neuropsychological performance

@article{Onnink2015DeviantWM,
  title={Deviant white matter structure in adults with attention-deficit/hyperactivity disorder points to aberrant myelination and affects neuropsychological performance},
  author={A Marten H Onnink and M. P. Zwiers and Martine Hoogman and Jeanette C. Mostert and Janneke Dammers and Cornelis C. Kan and Alejandro Arias V{\'a}squez and Aart H. Schene and Jan K. Buitelaar and Barbara Franke},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2015},
  volume={63},
  pages={14-22}
}
Attention-deficit/hyperactivity disorder (ADHD) in childhood is characterized by gray and white matter abnormalities in several brain areas. Considerably less is known about white matter microstructure in adults with ADHD and its relation with clinical symptoms and cognitive performance. In 107 adult ADHD patients and 109 gender-, age- and IQ-matched controls, we used diffusion tensor imaging (DTI) with tract-based spatial statistics (TBSS) to investigate whole-skeleton changes of fractional… CONTINUE READING