Developments in the management of autosomal dominant polycystic kidney disease

  title={Developments in the management of autosomal dominant polycystic
                    kidney disease},
  author={Amirali Masoumi and Berenice Reed-Gitomer and Catherine Kelleher and Mir Reza Bekheirnia and Robert Schrier},
  journal={Therapeutics and Clinical Risk Management},
  pages={393 - 407}
Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent life- threatening, hereditary disease. ADPKD is more common than sickle cell anemia, cystic fibrosis, muscular dystrophy, hemophilia, Down's syndrome, and Huntington's disease combined. ADPKD is a multisystemic disorder characterized by the progressive development of renal cysts and marked renal enlargement. Structural and functional renal deterioration occurs in ADPKD patients and is the fourth leading cause of end-stage… CONTINUE READING
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