Developmentally regulated postsynaptic localization of a metabotropic glutamate receptor in rat rod bipolar cells

@article{Nomura1994DevelopmentallyRP,
  title={Developmentally regulated postsynaptic localization of a metabotropic glutamate receptor in rat rod bipolar cells},
  author={Akinori Nomura and Ryuichi Shigemoto and Yasuhisa Nakamura and Naoyuki Okamoto and Shigetada Nakanishi},
  journal={Cell},
  year={1994},
  volume={77},
  pages={361-369}
}
The retinal bipolar cell receiving glutamate transmission from photoreceptors mediates a key process in segregating visual signals into ON center and OFF center pathways. This transmission involves a G protein-coupled metabotropic glutamate receptor (mGluR). Immunocytochemical and immunoelectron microscopic studies indicate that restricted localization of a specific mGluR subtype, mGluR6, at the postsynaptic site of the rat rod bipolar cell. This specialization is developmentally regulated… CONTINUE READING

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